Joe Rogan Experience #2149 - Sebastian Maniscalco

Sebastian Maniscalco makes his return to the Joe Rogan Experience and the two riff at length on the modern health-and-wellness obsession, with Joe defending his cold plunge, sauna, supplement and Eight Sleep routine while Sebastian plays the skeptical 50-year-old who tries trends on a whim. They dig into aging, sleep, late-night eating, and Sebastian's mystery detached biceps and sciatica. A long middle stretch breaks down the Mike Tyson vs Jake Paul fight, Tyson's terrifying prime, and the science of older fighters. They close on entertainment shifting to phones and podcasts, the violence on airplanes, and Sebastian weighing a move out of Los Angeles after Joe's pandemic-era relocation to Austin.

• Joe explains that people with the ABCC11 non-functioning gene variant have dry earwax and little to no body odor, which Sebastian believes describes him.
  00:19:44
• Joe argues modern 58-year-olds like Tyson aren't comparable to past generations because of hormone replacement, nutrition, and recovery science.
  01:16:35
• Joe declares prime Mike Tyson the best heavyweight of all time, better than even prime Ali.
  01:22:48
• Joe states the Tyson-Paul bout is a real professional fight that counts on their records, not an exhibition like the Roy Jones Jr fight.
  01:33:49
• Joe reveals he physically shrank the studio table because the second Mike Tyson podcast left him too nervous sitting close to him.
  01:40:35
• Joe recounts deciding to flee Los Angeles in May 2020 over pandemic lockdowns and unrest, moving to Austin by August.
  02:03:32
• Sebastian reveals he detached both biceps tendons with no trauma or pain, only noticing a hole in his arm in the mirror.
  01:40:35

• Will Harris of White Oak Pastures gave Joe two jars of soil, one regenerative and one dead industrial, displayed in the studio.
  00:02:06
• Andrew Huberman research cited shows a brief post-meal walk can change blood sugar levels by around 30-35%.
  00:23:53
• A 20-year Finland study found sauna use four times a week for 20 minutes lowers all-cause mortality by 40%.
  00:29:08
• The float tank works as a magnesium source because it contains about a thousand pounds of Epsom salts the skin absorbs.
  00:32:18
• Joe credits Adam Curry, the former MTV VJ, as the original 'podfather' who started podcasting off radio.
  00:52:37
• In the We Are the World footage Kenny Rogers was 47 and Willie Nelson 52, illustrating how aging has changed.
  01:18:07
• Bas Rutten began in Japan's Pancrase, where palm-strike slaps were legal and he KO'd opponents with uppercut palm strikes.
  01:35:56
• Dutch Muay Thai legend Ramon Dekkers shattered his ankle so often kicking that he had it surgically fused to keep fighting.
  01:37:29
• A schizophrenic passenger fashioned a weapon from pens and rubber bands and stabbed a fellow traveler on a Seattle-to-Vegas flight.
  01:11:53

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