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Diary of a CEO · 2023-02-20 · 1h 50m

The Health Expert: The One Food (WE ALL EAT) That's Killing Us Slowly: Max Lugavere | E223

Brain-food expert Max Lugavere on sugar, ultra-processed foods, red meat, the ketogenic diet, mental health, and aging well.

The Health Expert: The One Food (WE ALL EAT) That's Killing Us Slowly: Max Lugavere | E223
The guest

Max Lugavere — Health and science journalist, filmmaker, and author of the New York Times bestselling books Genius Foods and The Genius Life, focused on brain health and nutrition after his mother's neurodegenerative illness.

The gist

Max Lugavere shares how his mother's diagnosis with a neurodegenerative condition launched his decade-long obsession with nutrition and brain health. He breaks down why added sugar and ultra-processed foods are uniquely harmful, why he believes red meat and animal products are nutrient-dense and unfairly maligned, and the contexts where the ketogenic diet is therapeutically powerful. He discusses diet's role in mental health, hormetic stressors like saunas, circadian biology and meal timing, and the protective effects of coffee. The conversation closes on the cognitive cost of routine ('Groundhog Day syndrome') and a candid discussion of Max's childhood, attachment style, and relationships.

Big reveals

  • Max's vegetarian mother got sick fast and passed away; he reveals there were times he thought about suicide during the ordeal.
  • His mother was diagnosed at the Cleveland Clinic and prescribed drugs for both Alzheimer's and Parkinson's at the same time.
  • Vegan diets are associated with at least a doubling of depression risk, which Max attributes partly to missing animal-product nutrients.
  • Max reveals he is single and has been in therapy for over a year working on an avoidant attachment style.
  • He discloses experiencing 'covert incest' as a child, becoming his mother's emotional surrogate, which he links to his commitment difficulties.
  • Caffeine in coffee acts like a natural PCSK9 inhibitor, helping the liver recycle LDL cholesterol at around 400mg doses.
  • Pringles lack all three satiating characteristics (protein, fiber, water), explaining the 'once you pop you can't stop' effect.

Things worth remembering

  • The average adult consumes roughly 77 grams (almost 20 teaspoons) of added sugar every single day.
  • This is the first time in human history that there are more overweight people than underweight people on the planet.
  • In Alzheimer's disease the brain's ability to generate ATP from glucose is diminished by about 50 percent.
  • One in four people globally are anemic, and half of those cases are due to iron deficiency.
  • Using a sauna 2-3 times a week is linked to a 22% dementia risk reduction; 4-7 times a week to a 65% reduction.
  • The brain uses about 25% of basal metabolic rate despite being only 2-3% of body mass.
  • Synthetic emulsifiers polysorbate 80 and carboxymethylcellulose degrade the gut mucosa in animal models.
  • Beef liver is one of the best food sources of folate, and low folate is associated with depression.
  • The SMILES trial showed a roughly threefold increase in depression remission from a Mediterranean-style dietary intervention.

Recommended in this episode

Books, products and media the guest or host genuinely endorsed here — with the buy link.

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Guest’s ownBook

Genius Foods

Max Lugavere

“he's the author of The New York Times best-selling book genius Foods a brain food expert” — Diary of a CEO 00:00:08
Find it on Amazon
Guest’s ownBook

The Genius Life

Max Lugavere

“it was in your book The Genius life where you talk about this study with the mice and you make the case that travel” — Diary of a CEO 01:21:43
Find it on Amazon