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Joe Rogan · 2026-04-29 · 2h 32m

Joe Rogan Experience #2491 - Brian Simpson

Joe Rogan and comedian Brian Simpson riff on Brian's recent heart attack, pets and predators, gaming, nicotine science, crypto scams, and cosmic mysteries.

Joe Rogan Experience #2491 - Brian Simpson
The guest

Brian Simpson — Stand-up comedian and Army veteran, a regular at the Comedy Mothership in Austin. Known for his deadpan delivery and a podcast/streaming-adjacent life as a hardcore gamer.

The gist

A loose, wide-ranging conversation that opens with Brian recounting the heart attack he had on Super Bowl weekend in Atlanta and how he coped through humor. They drift through dogs, cats, coyotes and bears, then into Brian's deep gaming obsession (Deadlock, elaborate PC setups, streaming as a business). A long middle stretch dissects nicotine and smoking, including a controversial claim that smoking may correlate with longevity in blue zones if paired with the right diet. The back half turns to crypto pump-and-dump schemes, Ponzi scams targeting the elderly, insider trading in Congress, a Florida neighbor war over a guest house, and finally cosmic wonders like new telescopes, impossibly large black holes, the Great Attractor, and alleged megastructures beneath the Egyptian pyramids.

Big reveals

  • Joe says red light therapy plus Pure Encapsulations Macular Support fixed his eyesight so he no longer needs reading glasses.
  • Brian reveals he had a heart attack three months ago on Super Bowl weekend in Atlanta.
  • Joe says quitting cigarettes after his own heart attack was easy because he already felt terrible.
  • Joe shares a surgeon's controversial claim that nicotine can benefit longevity if paired with a high-polyphenol diet.
  • Joe walks through a hypothetical of using a crypto pump-and-dump as a legal way to bribe someone.
  • Joe describes radio-tomography scans showing alleged megastructures over a kilometer deep beneath the pyramids.

Things worth remembering

  • When a coyote goes missing from a pack's roll call, females respond by producing larger litters.
  • A 60-year Russian fox-domestication experiment bred dog-like silver foxes through selecting only for tameness.
  • T-Pain reportedly pulls in roughly a quarter-million dollars a month from streaming, sometimes just talking.
  • In parts of Sardinia, 95% of men smoke yet reportedly outlive the women, per Dr. Gundry's claim.
  • Cigarette packs hold 20 because that's calculated to maximize how many a person smokes in a day.
  • The Trump meme coin spiked to ~$75 then crashed; ~800,000 wallets collectively lost around $2 billion.
  • Outliers credits the Beatles' skill to relentless reps performing long sets in Hamburg clubs.
  • Judges hand down harsher sentences the longer it has been since they last ate.
  • The Great Attractor is pulling the Milky Way and ~100,000 galaxies toward something we can't see.
  • A new super-syphilis emerged in Washington after one man carried two strains that recombined.

Recommended in this episode

Books, products and media the guest or host genuinely endorsed here — with the buy link.

Affiliate link — we may earn a commission at no extra cost to you.

RecommendedProduct

Pure Encapsulations Macular Support

Pure Encapsulations

“the first thing I started doing is taking uh this company pure encapsulation has this um it's called uh macular support. It's like a combination of nutrients that help your eyeballs.” — Joe Rogan 00:00:32
Find it on Amazon
RecommendedBook

Coyote America

Dan Flores (inferred)

“There's a great book on it called Coyote America. yeah. It's really good. And um it's uh all about how coyotes” — Joe Rogan 00:24:17
Find it on Amazon
RecommendedMedia

Deadlock

Valve (inferred)

“Right now the game I'm playing the most is called Deadlock. It's not It's not avail It's not open available to the public.” — Brian Simpson 00:42:30
Find it on Amazon
RecommendedMedia

The Insider

Michael Mann (inferred)

“remember that Russell Crow movie, The Insider, you remember that movie? Good movie. It's about got about a guy who works at a tobacco company” — Joe Rogan 01:21:42
Find it on Amazon
RecommendedBook

Outliers

Malcolm Gladwell

“Outliers. great book. It's a really good book. It talks about like why people are successful.” — Joe Rogan 01:56:53
Find it on Amazon